Germany’s 4th ZAP-X Radiosurgery System to Advance Patient-Centered Brain Tumor Care at Alfried Krupp Hospital

World-class interdisciplinary team in Essen brings breakthrough, non-invasive radiosurgical treatments to North Rhine-Westphalia and beyond
A team of engineers stands proudly in front of the ZAP-X® Gyroscopic Radiosurgery system, an advanced, self-shielded radiosurgery platform designed for non-invasive brain tumor treatment. The image captures the innovative spirit behind ZAP Surgical Systems, showcasing the precision engineering and teamwork that drive the development of cutting-edge stereotactic radiosurgery (SRS) technology.
The ZAP-X® Gyroscopic Radiosurgery® platform, offering state-of-the-art brain tumor surgery without incisions, without pain.

San Carlos, CA – November 5, 2025 – ZAP Surgical Systems, Inc., a global leader in non-invasive robotic brain surgery, today announced the upcoming installation of its ZAP-X® Gyroscopic Radiosurgery® platform at the renowned Alfried Krupp von Bohlen und Halbach Krankenhaus in Essen, Germany. This will mark the fourth ZAP-X system in Germany and one of the first 30 worldwide, further solidifying the country’s leadership in adopting next-generation radiosurgical technologies.

Scheduled to begin treating patients in 2026, the ZAP-X system in Essen will be operated on an interdisciplinary basis by an esteemed team of specialists: Prof. Dr. Florian Ebner, Dr. Winfried Hohenhorst, Dr. Birgit Jäger and Prof. Dr. René Chapot. These experts, representing neurosurgery, otorhinolaryngology, radio-oncology and neuroradiology, aim to deliver fully integrated and personalized treatments utilizing the most advanced medical technologies available.

The image shows the ZAP-X® Gyroscopic Radiosurgery system, an innovative, self-shielded medical device designed for non-invasive brain tumor treatment. The gyroscopic design enables precise, targeted stereotactic radiosurgery (SRS) without the need for a traditional radiation vault. Next to the unit is the control console displaying detailed cranial imaging scans, illustrating the advanced technology behind ZAP Surgical Systems’ next-generation radiosurgery solution.
The ZAP-X® Gyroscopic Radiosurgery® platform, offering state-of-the-art brain tumor surgery without incisions, without pain.

As an alternative for open surgery for many patients, stereotactic radiosurgery (SRS) has emerged as a game-changer for treating many primary and metastatic brain tumors, as well as functional and vascular brain disorders. As a non-invasive, outpatient procedure typically completed in a single session without incision or anesthesia, SRS frequently enables patients to quickly resume their normal activities—often the same day.

Alfried Krupp Hospital in Essen, Germany, featuring the main entrance of the modern medical facility with people walking across a crosswalk on a sunny day.
Alfried Krupp Hospital, Essen, Germany.
The primary gantry ring of the ZAP-X® Gyroscopic Radiosurgery system being installed at Alfried Krupp Hospital in Essen, Germany, as it is lowered into its vault-free treatment suite through the hospital’s roof opening.
The primary gantry ring of the ZAP-X® Gyroscopic Radiosurgery® platform being lowered into its future vault-free treatment suite.

“Treatment with ZAP-X is a highly precise radiosurgery procedure. It is primarily performed in a single brief session, during which patients do not require anesthesia, as the procedure is painless. Patients can go home the same day of treatment,” said Prof. Dr. med. Dr. (Univ. Verona) Florian Ebner, Chief Physician, Department of Neurosurgery, Head of the DKG-certified Neuro-Oncological Center. “This project once again underscores the high level of innovation our hospitals offer for the benefit of patients”

“With ZAP-X, it is possible to treat the smallest tumors in just one session – even in the immediate vicinity of organs at risk and other structures that need to be protected,” states Dr. Birgit Jäger, Medical Director, Department of Radiooncology and Radiotherapy. “By implementing advanced medical technology, we can set new standards in patient care.”

The ZAP-X system uniquely harnesses gyroscopic mobility to direct radiation beams from thousands of potential angles, optimizing dose precision and minimizing exposure to healthy tissue. This capability is especially valuable when treating near critical structures like the brain stem and optic nerves, helping preserve patient cognitive function and quality of life.

ZAP-X is also the first and only dedicated cranial radiosurgery system that does not require a radiation-shielded treatment vault, enabling installation in locations previously deemed unfeasible. Moreover, by using a modern linear accelerator instead of Cobalt-60 sources, ZAP-X eliminates the need for costly radioactive isotope management—enhancing safety and sustainability.

“ZAP-X doesn’t have to be hidden behind meter-thick walls. Instead, we can offer patients a comfortable, bright treatment environment with access to natural light and the hospital’s atrium,” added Dr. rer. medic. Mark Oehmigen, Head of Medical Technology, Alfried Krupp Hospital.

For patients in Essen, across North Rhine-Westphalia, and throughout Germany, the upcoming ZAP-X system offers new possibilities for highly personalized, cutting-edge care in coordination with referring oncology centers.


About ZAP Surgical Systems, Inc.

ZAP Surgical Systems, Inc. designs and manufactures the ZAP-X® Gyroscopic Radiosurgery® platform. ZAP was founded in 2014 by Dr. John R. Adler, Emeritus Dorothy & TK Chan Professor of Neurosurgery and Radiation Oncology at Stanford University. Dr. Adler is also renowned as the inventor of the CyberKnife® system and founder of Accuray, Inc. The ZAP-X platform incorporates a unique vault-free design that typically eliminates the need for costly shielded treatment rooms. ZAP-X also utilizes a modern linear accelerator to eliminate legacy use of Cobalt-60. Learn more at www.zapsurgical.com and follow us on LinkedIn.

Contact:
Mark Arnold, ZAP Surgical Systems, Inc.
Senior Vice President, Marketing
+1 650 492 7797, ext. 101

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